Proteoglycan 3

Definition:

Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.

References:

[1]. D A Plager, et al. A novel and highly divergent homolog of human eosinophil granule major basic protein. J Biol Chem. 1999 May 14;274(20):14464-73. [Content Brief]

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