Pterin-4-alpha-carbinolamine dehydratase 2

Definition:

Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity).; Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.

References:

[1]. Seunghwan Lim, et al. Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. J Biol Chem. 2002 Jul 12;277(28):25040-6. [Content Brief]

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