RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Definition:

Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

References:

[1]. Benoit St-Pierre, et al. Conserved and specific functions of mammalian ssu72. Nucleic Acids Res. 2005 Jan 19;33(2):464-77. [Content Brief]

[2]. Kehui Xiang, et al. Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature. 2010 Oct 7;467(7316):729-33. [Content Brief]

[3]. Kehui Xiang, et al. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes Dev. 2012 Oct 15;26(20):2265-70. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.