StAR-related lipid transfer protein 8

Definition:

Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1.

References:

[1]. Katsuhisa Kawai, et al. START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology. Biochem Biophys Res Commun. 2007 Dec 28;364(4):783-9. [Content Brief]

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