Sushi domain-containing protein 6

Definition:

May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset (By similarity).

References:

[1]. Dagmar Schwanzer-Pfeiffer, et al. Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell culture model of endotoxemia. Cell Immunol. 2010;263(1):65-70. [Content Brief]

[2]. Federica Polato, et al. DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]. J Natl Cancer Inst. 2014 Apr;106(4):dju053. [Content Brief]

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