The HER-2 receptor tyrosine kinase

Definition:

The HER-2 receptor tyrosine kinase is an important regulator of cell proliferation and survival, and it is a target of therapeutic intervention for HER-2 positive breast cancer.

References:

[1]. Xiangdong Liu, et al. Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab. Cancer Biol Ther. 2006 Jun;5(6):648-56. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

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