TNF-related apoptosis-inducing ligand (TRAIL)

Definition:

TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and has been shown to induce apoptosis in cancer cells but not normal cells.

References:

[1]. Wang S, et al. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene. 2008 Oct 20;27(48):6207-15. [Content Brief]

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