Transcription factor JunD

Definition:

Transcription factor binding AP-1 sites. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing their transcriptional activity.

References:

[1]. Zhou Yin, et al. Activator Protein-1: redox switch controlling structure and DNA-binding. Nucleic Acids Res. 2017 Nov 2;45(19):11425-11436. [Content Brief]

[2]. S K Agarwal, et al. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell. 1999 Jan 8;96(1):143-52. [Content Brief]

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