Transmembrane protein 18

Definition:

Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).

References:

[1]. Jaana M Jurvansuu, et al. Obesity risk gene TMEM18 encodes a sequence-specific DNA-binding protein. PLoS One. 2011;6(9):e25317. [Content Brief]

[2]. Jaana Jurvansuu, et al. Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells. Cancer Res. 2008 Jun 15;68(12):4614-22. [Content Brief]

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