Tumor microenvironment (TME)

Definition:

Tumor microenvironment (TME) is the environment around a tumor. TME consists of tumor cells, tumor stromal cells including stromal fibroblasts, endothelial cells and immune cells like microglia, macrophages and lymphocytes, as well as the non-cellular components of extracellular matrix such as collagen, fibronectin, hyaluronan, laminin.

References:

[1]. Baghban R, et al. Tumor microenvironment complexity and therapeutic implications at a glance. Cell Commun Signal. 2020 Apr 7;18(1):59. [Content Brief]

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