Tumor necrosis factor ligand superfamily member 9

Definition:

Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

References:

[1]. Eun-Young Won, et al. The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily. J Biol Chem. 2010 Mar 19;285(12):9202-10. [Content Brief]

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