Vacuolar protein sorting-associated protein 37A

Definition:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

References:

[1]. Kristi G Bache, et al. The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. Mol Biol Cell. 2004 Sep;15(9):4337-46. [Content Brief]

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