1. Biology Dictionary
  2. Ventricular zone-expressed PH domain-containing protein homolog 1

Ventricular zone-expressed PH domain-containing protein homolog 1

Definition:

Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.

Biomedical Dictionary

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