ZZ-type zinc finger-containing protein 3

Definition:

Histone H3 reader that is required for the ATAC complex-mediated maintenance of histone acetylation and gene activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

References:

[1]. Sebastián Guelman, et al. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009 Mar;29(5):1176-88. [Content Brief]

[2]. Wenyi Mi, et al. The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation. Nat Commun. 2018 Sep 14;9(1):3759. [Content Brief]

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