2. PROTAC
  3. PROTAC Linkers
  4. Biotin-PEG8-NHS ester

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotin-PEG8-NHS ester Chemical Structure

Biotin-PEG8-NHS ester Chemical Structure

CAS No. : 2143968-03-8

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25 mg USD 145 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 mg USD 235 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 mg USD 380 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
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Based on 1 publication(s) in Google Scholar

Biotin-PEG8-NHS ester Related Antibodies

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Description

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Biotin-PEG8-NHS ester Related Antibodies
Molecular Weight

764.88

Formula

C33H56N4O14S
CAS No.
SMILES

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Biotin-PEG8-NHS ester Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-PEG8-NHS ester2143968-03-8PROTAC LinkersInhibitorinhibitorinhibit

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