Bis-propargyl-PEG6 

Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates^[1]. Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates which can be used as reagents for signal transduction research and as modulators of cyclic nucleotide-regulated binding proteins and isoenzymes thereof, and as ligands for affinity chromatography, for antibody production or for diagnostic applications e.g. on chip surfaces^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

358.43

C₁₈H₃₀O₇

400775-35-1

Solid-Liquid Mixture

Colorless to light yellow

C#CCOCCOCCOCCOCCOCCOCCOCC#C

Room temperature in continental US; may vary elsewhere.

• [1]. Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1.