2. PROTAC
  3. PROTAC Linkers
  4. Boc-12-Ado-OH

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

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Boc-12-Ado-OH Chemical Structure

Boc-12-Ado-OH Chemical Structure

CAS No. : 18934-81-1

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Boc-12-Ado-OH Related Antibodies

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Description

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Molecular Weight

315.45

Formula

C17H33NO4
CAS No.
Appearance

Solid

SMILES

CC(OC(NCCCCCCCCCCCC(O)=O)=O)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
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Boc-12-Ado-OH Related Classifications

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Keywords:

Boc-12-Ado-OH18934-81-1PROTAC LinkersInhibitorinhibitorinhibit

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