2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Boc-Val-Cit-OH

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Boc-Val-Cit-OH Chemical Structure

Boc-Val-Cit-OH Chemical Structure

CAS No. : 870487-08-4

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Based on 1 publication(s) in Google Scholar

Boc-Val-Cit-OH Related Antibodies

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Description

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Protease Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-Val-Cit-OH Related Antibodies
Molecular Weight

374.43

Formula

C16H30N4O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (245 KB) HNMR (146 KB)

Handling Instructions (2659 KB)
References
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Boc-Val-Cit-OH Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Val-Cit-OH870487-08-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
Boc-Val-Cit-OH
Cat. No.:
HY-W038702
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