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  4. Bone Gla Protein (45-49)

Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo.

For research use only. We do not sell to patients.

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Bone Gla Protein (45-49) Chemical Structure

Bone Gla Protein (45-49) Chemical Structure

CAS No. : 85679-70-5

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Description

Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo[1].

In Vitro

Bovine bone Gla protein (BGP) (1 nM-10 μM) exerts chemotactic activity of (0.1 and 1 μM) cultured human breast cancer cells (MDA-MB-231 cells), (1 nM-1 μM) human peripheral blood monocytes, and (1-10 μM) rat osteosarcoma cells with osteoblast-like characteristics[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

581.66

Formula

C30H39N5O7

CAS No.
Sequence Shortening

FYGPV

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Bone Gla Protein (45-49) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Bone Gla Protein (45-49)
Cat. No.:
HY-P3735
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