2. PROTAC Protein Tyrosine Kinase/RTK
  3. Ligands for Target Protein for PROTAC Btk
  4. BTK ligand 1

BTK ligand 1 (compound 1) is a ligand targeting Bruton’s tyrosine kinase (Btk). BTK ligand 1 can combine with E3 ligase ligand (Ligand for E3 Ligase) through PROTAC Linker to form PROTAC. PROTACs targeting Btk can be used in the study of chronic lymphocytic leukemia (CLL) and other BK cell malignancies.

For research use only. We do not sell to patients.

BTK ligand 1 Chemical Structure

BTK ligand 1 Chemical Structure

CAS No. : 330785-90-5

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Based on 1 publication(s) in Google Scholar

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BTK ligand 1 Related Antibodies

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Description

BTK ligand 1 (compound 1) is a ligand targeting Bruton’s tyrosine kinase (Btk). BTK ligand 1 can combine with E3 ligase ligand (Ligand for E3 Ligase) through PROTAC Linker to form PROTAC. PROTACs targeting Btk can be used in the study of chronic lymphocytic leukemia (CLL) and other BK cell malignancies[1].

Molecular Weight

386.45

Formula

C22H22N6O
CAS No.
SMILES

NC1=NC=NC2=C1C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN2C5CCNCC5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BTK ligand 1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BTK ligand 1330785-90-5BTK ligand1BTK ligand-1Ligands for Target Protein for PROTACBtkTarget Protein-binding MoietyBruton tyrosine kinaseCLLBK cellPROTACcancertumormalignanciesInhibitorinhibitorinhibit

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