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  3. BuChE-IN-14

BuChE-IN-14 is a novel compound that selectively inhibits acetylcholinesterase (AChE) activity. BuChE-IN-14 showed a concentration-dependent inhibitory effect on AChE in rat brain in vitro experiments. BuChE-IN-14 can increase the extracellular acetylcholine (ACh) concentration in the rat hippocampus and striatum at a certain dose. BuChE-IN-14 may help improve memory impairment caused by cholinergic dysfunction.

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BuChE-IN-14 Chemical Structure

BuChE-IN-14 Chemical Structure

CAS No. : 38455-99-1

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Description

BuChE-IN-14 is a novel compound that selectively inhibits acetylcholinesterase (AChE) activity. BuChE-IN-14 showed a concentration-dependent inhibitory effect on AChE in rat brain in vitro experiments. BuChE-IN-14 can increase the extracellular acetylcholine (ACh) concentration in the rat hippocampus and striatum at a certain dose. BuChE-IN-14 may help improve memory impairment caused by cholinergic dysfunction[1].

Molecular Weight

598.15

Formula

C31H36ClN3O5S

CAS No.
SMILES

O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCCN2CCN(CCCN3C4=C(SC5=CC(Cl)=CC=C53)C=CC=C4)CC2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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BuChE-IN-14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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BuChE-IN-14
Cat. No.:
HY-168167
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