2. Protein Tyrosine Kinase/RTK Epigenetics Cell Cycle/DNA Damage Apoptosis
  3. c-Met/HGFR HDAC Apoptosis
  4. c-Met/HDAC-IN-4

c-Met/HDAC-IN-4 is a dual inhibitor of c-Met/HDAC. The IC50 value of c-Met/HDAC-IN-4 for c-Met is 28.92 nM. c-Met/HDAC-IN-4 can induce G0/G1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells, and it inhibits the proliferation and invasion of breast cancer cell lines.

For research use only. We do not sell to patients.

c-Met/HDAC-IN-4 Chemical Structure

c-Met/HDAC-IN-4 Chemical Structure

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c-Met/HDAC-IN-4 Related Antibodies

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Description

c-Met/HDAC-IN-4 is a dual inhibitor of c-Met/HDAC. The IC50 value of c-Met/HDAC-IN-4 for c-Met is 28.92 nM. c-Met/HDAC-IN-4 can induce G0/G1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells, and it inhibits the proliferation and invasion of breast cancer cell lines[1].
Molecular Weight

608.73

Formula

C37H36N8O
SMILES

NC1=CC=CC=C1NC(/C=C/C2=CC=C(CN3CCN(C4=CC=C(N=NN5C(C6=CC=C(N=CC=C7)C7=C6)C)C5=C4)CC3)C=C2)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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c-Met/HDAC-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Met/HDAC-IN-4c-Met/HGFRHDACApoptosisHistone deacetylasesc-Met/HDACMDA-MB-231cell cycle arrestapoptosisInhibitorinhibitorinhibit

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