2. Apoptosis
  3. c-Myc
  4. c-Myc inhibitor 8

c-Myc inhibitor 8 (compound 56) is a c-Myc inhibitor. c-Myc inhibitor 8 effectively inhibits cell viability of a variety of cancer cells. c-Myc inhibitor 8 inhibits human prostate and lung cancer growth in mouse models. c-Myc inhibitor 8 can be used for cancer research.

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c-Myc inhibitor 8 Chemical Structure

c-Myc inhibitor 8 Chemical Structure

CAS No. : 2173505-97-8

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c-Myc inhibitor 8 Related Antibodies

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Description

c-Myc inhibitor 8 (compound 56) is a c-Myc inhibitor. c-Myc inhibitor 8 effectively inhibits cell viability of a variety of cancer cells. c-Myc inhibitor 8 inhibits human prostate and lung cancer growth in mouse models. c-Myc inhibitor 8 can be used for cancer research[1].

In Vitro

c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of KU-19-19, 253J, J82, Τ24, ΜΒΤ-2 and UM-UC-3 bladder cancer cell lines with IC50s of 0.90, 1.11, 1.46, 0.98, 1.18 and 1.25 μM, respectively[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of Α549, NCI-H460, MRC-5 and NCI-H23 hepatoma cell lines with IC50s of 1.70, 1.90, 1.24 and 1.04 μM, respectively[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of MDA-MB-231, SK-BR-3, HCC1954 and MDA-MB-468 breast cancer cell lines with IC50s of 1.45, 1.38, 1.47 and 1.64 μM, respectively[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of HL-60, U-937, Raji, Ramos (RAl), Daudi, Jurkat, MV-4-11 and MOLT-4 blood cancer cell lines with IC50s of 1.95, 1.75, 1.12, 1.86, 1.25, 1.06, 1.50 and 1.66 μM, respectively[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of ΜΙΑ PaCa-2 pancreatic cancer cell line with an IC50 of 1.37 μM[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of HCT 116, SW620, HCT-15, RKO, HCT-8 and DLD-I colorectal cancer cell lines with IC50s of 1.19, 1.91, 1.32, 1.53, 1.69 and 0.80 μM, respectively[1].
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of U-251 MG, U-138 MG, LOX-IMVI, SK-HEP-I and OVCAR-3 cancer cell lines with IC50s of 1.17, 1.34, 1.09, 1.02 and 1.09 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

c-Myc inhibitor 8 Related Antibodies
In Vivo

c-Myc inhibitor 8 (10 mg/kg; intraperitoneal injection, 3 times a week, for 10 days) inhibits tumor growth of human NCI-H1299 lung cancer mouse models[1].
c-Myc inhibitor 8 (30 mg/kg; intraperitoneal injection, 2 times a week, for 13 days) inhibits tumor growth of human prostate DU 145 cancer mouse models[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

538.79

Formula

C19H12BrClF3NO3S2
CAS No.
SMILES

O=C1C2=C(NC(S(CC3=CC=C(C=C3)SC(F)(F)F)=O)=C1C(C)=O)C(Br)=CC=C2Cl
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Room temperature in continental US; may vary elsewhere.
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c-Myc inhibitor 8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Myc inhibitor 82173505-97-8c-MycMycbladderhepatomabreastbloodpancreaticcolorectalcancermouseInhibitorinhibitorinhibit

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