2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. CAIX/CAXII-IN-2

CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, with Ki values ​​of 8.9 nM and 5.3 nM for CAIX/CAXII, respectively. CAIX/CAXII-IN-2 can be used in cancer research.

For research use only. We do not sell to patients.

CAIX/CAXII-IN-2 Chemical Structure

CAIX/CAXII-IN-2 Chemical Structure

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CAIX/CAXII-IN-2 Related Antibodies

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Description

CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, with Ki values ​​of 8.9 nM and 5.3 nM for CAIX/CAXII, respectively. CAIX/CAXII-IN-2 can be used in cancer research[1].

IC50 & Target

hCA IX

8.9 nM (Ki)

hCA XII

5.3 nM (Ki)

In Vitro

CAIX/CAXII-IN-2 (compound 23) (0-1000 μM, 72h) inhibits the proliferation of MDA-MB-231 and U87MG cells, with the IC50 values ​​of 38.8 μM and 34 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAIX/CAXII-IN-2 Related Antibodies
Molecular Weight

326.37

Formula

C16H14N4O2S
SMILES

O=S(C1=CC=C(C2=NC(N)=NC(C3=CC=CC=C3)=C2)C=C1)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CAIX/CAXII-IN-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAIX/CAXII-IN-2Carbonic AnhydraseCarbonate dehydratasebenzenesulfonamide moiety,hypoxic tumorsInhibitorinhibitorinhibit

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