Calcitonin-¹³C₆,¹⁵N₄ (salmon) TFA  (Synonyms: Salmon calcitonin-¹³C₆,¹⁵N₄ TFA)

Calcitonin-¹³C₆,¹⁵N₄ (salmon) (Salmon calcitonin-¹³C₆,¹⁵N₄) TFA is ¹³C and ¹⁵N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption^[1].

4007.93

C₁₄₀¹³C₅H₂₄₀N₄₃¹⁵NO₄₈S₂.5C₂HF₃O₂

Solid

Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-{Arg-13C6,15N4}-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bridge: Cys1-Cys7)

CSNLSTCVLGKLSQELHKLQTYP-{Arg-13C6,15N4}-TNTGSGTP-NH2 (Disulfide bridge: Cys1-Cys7)

O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.OC1=CC=C(C[C@@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C([15N]3[13C@H]([13C](N)=O)[13CH2][13CH2][13CH2]3)=O)[C@@H](C)O)=O)=O)CO)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)CCC2)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H]5NC([C@]([H])([C@@H](C)O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@@H](N)CSSC5)=O)=O)=O)=O)=O)=O)=O)C(C)C)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CO)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)[C@@H](C)O)=O)C=C1.O=C(O)C(F)(F)F

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Feigh M, et al. Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats. Br J Pharmacol. 2012 Sep;167(1):151-63.  [Content Brief]