Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Synonyms: Ca-DTPA trisodium salt hydrate)

Cat. No.: HY-128370 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication.

For research use only. We do not sell to patients.

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Chemical Structure

CAS No. : 207226-35-5

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

The antiviral activity of Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is suppressed by metal ions with a decreasing potency order of Mn2+/Zn2+>Fe2+>Cu2+>Fe3+. Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate inhibits CMV L-antigen production with EC₅₀ ranging from 6.1 to 9.9 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

515.37

Formula

C₁₄H₂₀CaN₃Na₃O₁₁

CAS No.

207226-35-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])CN(CC([O-])=O)CCN(CC(O[Na])=O)CCN(CC(O[Na])=O)CC([O-])=O.[Ca+2].O.[x]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 175 mg/mL (339.56 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9404 mL	9.7018 mL	19.4035 mL
5 mM	0.3881 mL	1.9404 mL	3.8807 mL
10 mM	0.1940 mL	0.9702 mL	1.9404 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (254 KB) HNMR (263 KB) MS (69 KB)

Handling Instructions (2659 KB)

References

[1]. Eybl V, et al. Effect of cadmium chelating agents on organ cadmium and trace element levels in mice. Analyst. 1998;123(1):25-26. [Content Brief]

[2]. Cinatl J Jr, et al. In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid. Antiviral Res. 1996;31(1-2):23-34. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9404 mL	9.7018 mL	19.4035 mL	48.5088 mL
	5 mM	0.3881 mL	1.9404 mL	3.8807 mL	9.7018 mL
	10 mM	0.1940 mL	0.9702 mL	1.9404 mL	4.8509 mL
	15 mM	0.1294 mL	0.6468 mL	1.2936 mL	3.2339 mL
	20 mM	0.0970 mL	0.4851 mL	0.9702 mL	2.4254 mL
	25 mM	0.0776 mL	0.3881 mL	0.7761 mL	1.9404 mL
	30 mM	0.0647 mL	0.3234 mL	0.6468 mL	1.6170 mL
	40 mM	0.0485 mL	0.2425 mL	0.4851 mL	1.2127 mL
	50 mM	0.0388 mL	0.1940 mL	0.3881 mL	0.9702 mL
	60 mM	0.0323 mL	0.1617 mL	0.3234 mL	0.8085 mL
	80 mM	0.0243 mL	0.1213 mL	0.2425 mL	0.6064 mL
	100 mM	0.0194 mL	0.0970 mL	0.1940 mL	0.4851 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Calcium trinatrium diethylenetriaminepentaacetic acid207226-35-5Ca-DTPA trisodium saltCMVCytomegalovirusmetalreplicationantidotechelatorintoxicationInhibitorinhibitorinhibit

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