2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Photosensitizer Reactive Oxygen Species Ferroptosis
  4. CAR-2

CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models.

For research use only. We do not sell to patients.

CAR-2 Chemical Structure

CAR-2 Chemical Structure

CAS No. : 3030055-40-1

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CAR-2 Related Antibodies

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Description

CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models[1].

Molecular Weight

738.11

Formula

C27H23BF2I2N4O2
CAS No.
SMILES

O=C(C1=CC2=C(N(C3=CC=CC=C32)C)C(C4=C5[N+]([B-](F)(N6C4=C(C(I)=C6C)C)F)=C(C(I)=C5C)C)=N1)OC
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CAR-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAR-23030055-40-1CAR2CAR 2PhotosensitizerReactive Oxygen SpeciesFerroptosis4T1MDA-MB-231MCF-7Bcap-37photosensitizerInhibitorinhibitorinhibit

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