2. Others Anti-infection Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds HCV Protease HCV SARS-CoV
  4. 401815-65-4

401815-65-4

GW461484A Chemical Structure

401815-65-4

Chemical Structure

  • GW461484A
  • CAS No: 401815-65-4
    Formula: C19H14FN3
    Molecular Weight: 303.33
  • InChIKey: DLJKUEGEDDMTMQ-UHFFFAOYSA-N
  • SMILES: FC(C=C1)=CC=C1C2=NN3C(C=CC(C)=C3)=C2C4=CC=NC=C4

Biological Activity: GW461484A is a small-molecule inhibitor targeting Candida albicans Yck2, with an IC50 of 0.11 µM. It exhibits antifungal activity against C. albicans with a MIC80 of 12.5 µM. GW461484A holds potential for research on fungal diseases, such as drug-resistant Candida infections[1].

Cat. No. Product Name Purity Description
HY-172676 GW461484A GW461484A is a small-molecule inhibitor targeting Candida albicans Yck2, with an IC50 of 0.11 µM. It exhibits antifungal activity against C. albicans with a MIC80 of 12.5 µM. GW461484A holds potential for research on fungal diseases, such as drug-resistant Candida infections.

References

[1]. Puumala E, et al. Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans. Nat Commun. 2025 Mar 4;16(1):2156. [Content Brief]

Keywords:

GW461484A