2. GPCR/G Protein
  3. Endothelin Receptor
  4. 136286-50-5

136286-50-5

WS009B Chemical Structure

136286-50-5

Chemical Structure

  • WS009B
  • CAS No: 136286-50-5
    Formula: C24H25NO11S
    Molecular Weight: 535.52
  • IUPAC Name: N-acetyl-S-(4a,6,8,12a,12b-pentahydroxy-3-methyl-1,7,12-trioxo-4,4a,5,6,7,12,12a,12b-octahydrotetraphen-6a(1H)-yl)-L-cysteine
  • InChIKey: JTSMUTXXQIUBJR-FJOZLUQASA-N
  • SMILES: O=C(O)[C@H](CSC1(C(C2=C3C=CC=C2O)=O)C(O)CC(CC(C)=CC4=O)(O)C4(O)C1(O)C3=O)NC(C)=O

Biological Activity: WS009B is a selective endothelin receptor antagonist (ET-1: IC50=0.67 μM; ET-2: IC50=0.8 μM). WS009B can be used in the study of cardiovascular diseases[1].

Cat. No. Product Name Purity Description
HY-117634 WS009B WS009B is a selective endothelin receptor antagonist (ET-1: IC50=0.67 μM; ET-2: IC50=0.8 μM). WS009B can be used in the study of cardiovascular diseases.

References

[1]. MIYATA S, et al. WS009 A and B, new endothelin receptor antagonists isolated from Streptomyces sp. No. 89009 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities[J]. The Journal of Antibiotics, 1992, 45(7): 1029-1040. [Content Brief]

Keywords:

WS009B