2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. 459848-10-3

459848-10-3

CID1172084 Chemical Structure

459848-10-3

Chemical Structure

  • CID1172084
  • CAS No: 459848-10-3
    Formula: C23H18FN5O2S2
    Molecular Weight: 479.55
  • IUPAC Name: N-(4-(4-fluorophenyl)thiazol-2-yl)-2-((8-methoxy-4-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio)acetamide
  • InChIKey: NQAXYXKWUOWLNN-UHFFFAOYSA-N
  • SMILES: O=C(CSC1=NN=C2N1C3=C(C=C2C)C=CC(OC)=C3)NC4=NC(C5=CC=C(C=C5)F)=CS4

Biological Activity: CID1172084 (compound 3) is a selective GPR55 agonist (EC50=0.16 μM). CID1172084 is more than 100-fold selective for GPR55 over GPR35, CB1, and CB2. CID1172084 can be used to further explore the biological functions and signaling pathways of the GPR55 receptor[1].

Cat. No. Product Name Purity Description
HY-123302 CID1172084 CID1172084 (compound 3) is a selective GPR55 agonist (EC50=0.16 μM). CID1172084 is more than 100-fold selective for GPR55 over GPR35, CB1, and CB2. CID1172084 can be used to further explore the biological functions and signaling pathways of the GPR55 receptor.

References

[1]. Kotsikorou, et al. "Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands." Biochemistry 50.25 (2011): 5633-5647 [Content Brief]

Keywords:

CID1172084