1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. 207390-14-5

207390-14-5

3-Bromocytisine Chemical Structure

207390-14-5

Chemical Structure

  • 3-Bromocytisine
  • Synonym(s): 3-Br-cytisine
  • CAS No: 207390-14-5
    Formula: C11H13BrN2O
    Molecular Weight: 269.14
  • IUPAC Name: (1R,5S)-9-bromo-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one
  • InChIKey: DWDCLEHDNICBMI-JGVFFNPUSA-N
  • SMILES: O=C1N2C([C@]3([H])C[C@](CNC3)([H])C2)=CC=C1Br

Biological Activity: 3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively[1][2].

Cat. No. Product Name Purity Description
HY-107684 3-Bromocytisine 99.90% 3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively.

References

Keywords:

3-Bromocytisine