1. PROTAC
  2. PROTAC Linkers
  3. 2144777-77-3

2144777-77-3

Azido-PEG5-CH2CO2-NHS Chemical Structure

2144777-77-3

Chemical Structure

  • Azido-PEG5-CH2CO2-NHS
  • CAS No: 2144777-77-3
    Formula: C16H26N4O9
    Molecular Weight: 418.40
  • IUPAC Name: 2,5-dioxopyrrolidin-1-yl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate
  • InChIKey: PKNZIAMWWCOXMJ-UHFFFAOYSA-N
  • SMILES: O=C(ON1C(CCC1=O)=O)COCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description
HY-140766 Azido-PEG5-CH2CO2-NHS Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References