2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 245660-13-3

245660-13-3

EpoY Chemical Structure

245660-13-3

Chemical Structure

  • EpoY
  • Synonym(s): SD-142
  • CAS No: 245660-13-3
    Formula: C15H17NO7
    Molecular Weight: 323.30
  • IUPAC Name: ((2S,3S)-3-(ethoxycarbonyl)oxirane-2-carbonyl)-L-tyrosine
  • InChIKey: PSLWNPKMALERSK-SRVKXCTJSA-N
  • SMILES: OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@@H]2[C@H](O2)C(OCC)=O)=O

Biological Activity: EpoY (SD-142) acts as an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition leads to significant differentiation defects and has been linked to underlying issues associated with cancer and cardiomyopathies.

Cat. No. Product Name Purity Description
HY-148542 EpoY 98.0% EpoY (SD-142) acts as an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition leads to significant differentiation defects and has been linked to underlying issues associated with cancer and cardiomyopathies.

Keywords:

EpoY