2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. 256640-46-7

256640-46-7

(S,S)-J-113397 Chemical Structure

256640-46-7

Chemical Structure

  • (S,S)-J-113397
  • CAS No: 256640-46-7
    Formula: C24H37N3O2
    Molecular Weight: 399.57
  • IUPAC Name: 1-((3S,4S)-1-(cyclooctylmethyl)-3-(hydroxymethyl)piperidin-4-yl)-3-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
  • InChIKey: MBGVUMXBUGIIBQ-RTWAWAEBSA-N
  • SMILES: O=C1N([C@@H]2[C@H](CN(CC2)CC3CCCCCCC3)CO)C4=CC=CC=C4N1CC

Biological Activity: (S,S)-J-113397 is an isomer of J-113397 (HY-114072). J-113397 is an Opioid Receptor antagonist[1].

Cat. No. Product Name Purity Description
HY-114072A (S,S)-J-113397 99.87% (S,S)-J-113397 is an isomer of J-113397 (HY-114072). J-113397 is an Opioid Receptor antagonist.

References

[1]. Kawamoto H, et al. Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3 R, 4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2 H-benzimidazol-2-one (J-113397)[J]. Journal of medicinal chemistry, 1999, 42(25): 5061-5063.

Keywords:

(S,S)-J-113397