1. PROTAC Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  2. PROTACs JAK
  3. 2921556-14-9

2921556-14-9

PROTAC TYK2 degradation agent1 Chemical Structure

2921556-14-9

Chemical Structure

  • PROTAC TYK2 degradation agent1
  • CAS No: 2921556-14-9
    Formula: C55H69N13O7S
    Molecular Weight: 1056.28
  • IUPAC Name: 6-((5-((10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecyl)carbamoyl)pyridin-2-yl)amino)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotin
  • InChIKey: ZQBPERKIXUCCNQ-DXGZDBETSA-N
  • SMILES: CNC(C1=CN=C(C=C1NC2=C(C(C3=NN(C=N3)C)=CC=C2)OC)NC4=CC=C(C=N4)C(NCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N5C[C@@H](C[C@H]5C(NCC6=CC=C(C=C6)C7=C(N=CS7)C)=O)O)=O)=O)=O)=O

Biological Activity: PROTAC TYK2 degradation agent1 is a potent and subtype-selective TYK2 degrader. PROTAC TYK2 degradation agent1 has TYK2 degradation activity with DC50 value of 14 nM. PROTAC TYK2 degradation agent1 can be used for the research of autoimmune disease[1].

Cat. No. Product Name Purity Description
HY-152227 PROTAC TYK2 degradation agent1 99.50% PROTAC TYK2 degradation agent1 is a potent and subtype-selective TYK2 degrader. PROTAC TYK2 degradation agent1 has TYK2 degradation activity with DC50 value of 14 nM. PROTAC TYK2 degradation agent1 can be used for the research of autoimmune disease.

References