1. Others Neuronal Signaling
  2. Drug Intermediate Cholinesterase (ChE)
  3. 4533-39-5

4533-39-5

Nitracrine Chemical Structure

4533-39-5

Chemical Structure

  • Nitracrine
  • CAS No: 4533-39-5
    Formula: C18H20N4O2
    Molecular Weight: 324.38
  • IUPAC Name: N1,N1-dimethyl-N3-(1-nitroacridin-9-yl)propane-1,3-diamine
  • InChIKey: YMVWGSQGCWCDGW-UHFFFAOYSA-N
  • SMILES: O=[N+](C1=CC=CC2=NC3=CC=CC=C3C(NCCCN(C)C)=C21)[O-]

Biological Activity: Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells[1][2][3].

Cat. No. Product Name Purity Description
HY-U00279 Nitracrine 97.76% Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells.

References

Keywords:

Nitracrine