2. Cell Cycle/DNA Damage PI3K/Akt/mTOR Apoptosis
  3. Polo-like Kinase (PLK) PI3K Apoptosis
  4. 91634-12-7

91634-12-7

STIMA-1 Chemical Structure

91634-12-7

Chemical Structure

  • STIMA-1
  • CAS No: 91634-12-7
    Formula: C10H8N2O
    Molecular Weight: 172.18
  • IUPAC Name: 2-vinylquinazolin-4(3H)-one
  • InChIKey: VCHFWHQHIKFOIC-UHFFFAOYSA-N
  • SMILES: O=C1NC(C=C)=NC2=C1C=CC=C2

Biological Activity: STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells[1].

Cat. No. Product Name Purity Description
HY-W034419 STIMA-1 99.94% STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells.

References

[1]. Nicole Zache, et al. Mutant p53 targeting by the low molecular weight compound STIMA-1. Mol Oncol. 2017 May;11(5):595. [Content Brief]

Keywords:

STIMA-1