2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. Opioid Receptor iGluR
  4. 38393-73-6

38393-73-6

OAT1/3-IN-1 Chemical Structure

38393-73-6

Chemical Structure

  • OAT1/3-IN-1
  • CAS No: 38393-73-6
    Formula: C16H12O6
    Molecular Weight: 300.26
  • InChIKey: RVURFFCNSWQLMO-UHFFFAOYSA-N
  • SMILES: O=C1C2=CC=C(C(O)=C2C(C3=C1C=C(C)C(O)=C3OC)=O)O

Biological Activity: OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage[1].

Cat. No. Product Name Purity Description
HY-N12007 OAT1/3-IN-1 OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage.

References

[1]. Wang X, et al. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. Toxicol Sci. 2018 Feb 1;161(2):321-334. [Content Brief]

Keywords:

OAT1/3-IN-1