2. Immunology/Inflammation
  3. NO Synthase
  4. 85697-89-8

85697-89-8

L-NAPNA Chemical Structure

85697-89-8

Chemical Structure

  • L-NAPNA
  • CAS No: 85697-89-8
    Formula: C12H17N7O5
    Molecular Weight: 339.31
  • IUPAC Name: (S)-2-amino-5-(3-nitroguanidino)-N-(4-nitrophenyl)pentanamide
  • InChIKey: LNWGWFVAPQTGMG-JTQLQIEISA-N
  • SMILES: O=C(NC1=CC=C([N+]([O-])=O)C=C1)[C@@H](N)CCCNC(N[N+]([O-])=O)=N

Biological Activity: L-NAPNA is a nitric oxide synthase (NOS) inhibitor with an IC50 of 1.4 μM. L-NAPNA exhibits analgesic effects by inhibiting formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and suppressing acetic acid-induced abdominal writhing in mice (ED50 of 25 mg/kg). L-NAPNA can be used in research related to central nervous system diseases[1].

Cat. No. Product Name Purity Description
HY-115889 L-NAPNA L-NAPNA is a nitric oxide synthase (NOS) inhibitor with an IC50 of 1.4 μM. L-NAPNA exhibits analgesic effects by inhibiting formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and suppressing acetic acid-induced abdominal writhing in mice (ED50 of 25 mg/kg). L-NAPNA can be used in research related to central nervous system diseases.

References

[1]. Babbedge RC, et al. L-NG-nitro arginine p-nitroanilide (L-NAPNA) is anti-nociceptive in the mouse. Neuroreport. 1993 Mar;4(3):307-10. [Content Brief]

Keywords:

L-NAPNA