2. PI3K/Akt/mTOR Apoptosis
  3. PI3K Apoptosis
  4. 902156-99-4

902156-99-4

NVP-LCQ195 Chemical Structure

902156-99-4

Chemical Structure

  • NVP-LCQ195
  • Synonym(s): LCQ-195; AT9311
  • CAS No: 902156-99-4
    Formula: C17H19Cl2N5O4S
    Molecular Weight: 460.33
  • IUPAC Name: 4-(2,6-dichlorobenzamido)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-5-carboxamide
  • InChIKey: CCUXEBOOTMDSAM-UHFFFAOYSA-N
  • SMILES: CS(=O)(N1CCC(NC(C2=C(NC(C3=C(Cl)C=CC=C3Cl)=O)C=NN2)=O)CC1)=O
Cat. No. Product Name Purity Description
HY-15241 NVP-LCQ195 98.81% NVP-LCQ195 (AT9311; LCQ195) is a small molecule heterocyclic inhibitor of CDK1, CDK2, CDK3 and CDK5 with IC50 of 1-42 nM.

References

McMillin DW, Delmore J, Negri J et al. Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications. Br J Haematol. 2011 Feb;152(4):420-32. [Content Brief]

Keywords:

NVP-LCQ195