2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. Casein kinase 1δ-IN-5

Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM. Casein kinase 1δ-IN-5 shows neuroprotective and anti-inflammatory properties both in vitro. Casein kinase 1δ-IN-5 has the potential for neurodegenerative diseases research.

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Casein kinase 1δ-IN-5 Chemical Structure

Casein kinase 1δ-IN-5 Chemical Structure

CAS No. : 1579991-10-8

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Casein kinase 1δ-IN-5 Related Antibodies

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Description

Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM. Casein kinase 1δ-IN-5 shows neuroprotective and anti-inflammatory properties both in vitro. Casein kinase 1δ-IN-5 has the potential for neurodegenerative diseases research.

IC50 & Target[1]

CK1δ

47 nM (IC50)

Molecular Weight

336.33

Formula

C16H11F3N2OS
CAS No.
SMILES

O=C(CC1=CC=CC=C1)NC2=NC3=C(S2)C=C(C(F)(F)F)C=C3
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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Casein kinase 1δ-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Casein kinase 1δ-IN-51579991-10-8Casein Kinaseanti-inflammatory agentneurodegenerative diseasePDSH-SY5YGlial Primary CultureNeuroprotectiveParkinson’s diseaselead compoundInhibitorinhibitorinhibit

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