2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Cavα2δ1&NET-IN-3

Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET). Cavα2δ1&NET-IN-3 has Kis of 100-500 nM for human α2δ-1 subunit of Cav2.2 calcium channel and NET, respectively.

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Cavα2δ1&NET-IN-3 Chemical Structure

Cavα2δ1&NET-IN-3 Chemical Structure

CAS No. : 2143584-82-9

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Cavα2δ1&NET-IN-3 Related Antibodies

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Description

Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET). Cavα2δ1&NET-IN-3 has Kis of 100-500 nM for human α2δ-1 subunit of Cav2.2 calcium channel and NET, respectively[1].

IC50 & Target[1]

Calcium Channel

 

Molecular Weight

466.60

Formula

C24H30N6O2S
CAS No.
SMILES

O=C1C2=CN=C(NCC)N=C2N(CCN1C3=CC(O[C@H](C4=CC=CS4)CCNC)=CC=C3)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cavα2δ1&NET-IN-3 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cavα2δ1&NET-IN-32143584-82-9Calcium ChannelCa2+ channelsCa channelsα2δvoltage-gated calcium channelsVGCCnoradrenaline transporterNETα2δ-1Cav2.2Inhibitorinhibitorinhibit

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