2. PROTAC
  3. Ligands for E3 Ligase
  4. Caylin-1

Caylin-1 is an inhibitor of MDM2 and an analog of Nutlin-3. Caylin-1 can bind to Bcl-XL and is used in multi-target anticancer research.

For research use only. We do not sell to patients.

Caylin-1 Chemical Structure

Caylin-1 Chemical Structure

CAS No. : 1207480-88-3

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Caylin-1 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP

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Description

Caylin-1 is an inhibitor of MDM2 and an analog of Nutlin-3. Caylin-1 can bind to Bcl-XL and is used in multi-target anticancer research[1][2].

Molecular Weight

650.38

Formula

C30H28Cl4N4O4
CAS No.
SMILES

O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C(Cl)=C3)[C@@H](C4=CC=C(Cl)C(Cl)=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Caylin-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caylin-11207480-88-3Caylin1Caylin 1Ligands for E3 LigaseE3 ligase-recruiting MoietyAnticancerInhibitorinhibitorinhibit

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