2. TGF-beta/Smad
  3. TGF-β Receptor
  4. CDD-1431

CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2, with Kiapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC50 of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation.

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CDD-1431 Chemical Structure

CDD-1431 Chemical Structure

CAS No. : 3034216-31-1

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CDD-1431 Related Antibodies

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Description

CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2, with Kiapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC50 of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation[1].

IC50 & Target

BMPR2: Kiapp value of 20.6 nM
Molecular Weight

658.77

Formula

C33H38N8O5S
CAS No.
SMILES

COC(C=N1)=C(N2CCN(C3=CC=CC(CNC(C4=CC=C(CCC(NC)=O)C=C4)=O)=C3)CC2)N=C1NC5=CC(S(=O)(N)=O)=CC=C5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDD-1431 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDD-14313034216-31-1CDD1431CDD 1431TGF-β ReceptorTransforming growth factor beta receptorsLiver microsomesHEK293THUVECs293T BRE-RInhibitorinhibitorinhibit

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