2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. CDKL2-IN-1

CDK-IN-14 (Compound 9) is a potent and selective CDKL2 (Cyclin-dependent kinase-like 2) inhibitor with an IC50 value of 460 nM. CDKL2 is involved in various biological processes such as tumorigenesis, development, and viral infections. CDK-IN-14 serves as a powerful tool for studying the biological functions of CDKL2 and holds promise for research in fields related to cancer, infections, and other diseases.

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CDKL2-IN-1 Chemical Structure

CDKL2-IN-1 Chemical Structure

CAS No. : 2471972-15-1

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CDKL2-IN-1 Related Antibodies

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Description

CDK-IN-14 (Compound 9) is a potent and selective CDKL2 (Cyclin-dependent kinase-like 2) inhibitor with an IC50 value of 460 nM. CDKL2 is involved in various biological processes such as tumorigenesis, development, and viral infections. CDK-IN-14 serves as a powerful tool for studying the biological functions of CDKL2 and holds promise for research in fields related to cancer, infections, and other diseases[1].

IC50 & Target

IC50: 460 nM (Cyclin-dependent kinase-like 2 (CDKL2))[1]
In Vitro

CDK-IN-14 (0-4 μM, 1 h) disrupts CDKL2-mediated downstream signaling in rat primary neurons by inhibiting CDKL2, and has an inhibitory effect on CDKL2 activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CDKL2-IN-1 Related Antibodies

Western Blot Analysis[1]

Cell Line: Rat primary neurons
Concentration: 0-4 μM
Incubation Time: 1 h
Result: Completely suppressed the CDKL2-mediated EB2 (microtubule end binding protein 2) phosphorylation in a dose-dependent manner.
Molecular Weight

426.53

Formula

C22H26N4O3S
CAS No.
SMILES

O=S(NCC1=CC(C2=CC(NN=C3NC(C4CC4)=O)=C3C=C2)=CC=C1)(CC(C)C)=O
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDKL2-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDKL2-IN-12471972-15-1Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesRat primary neuronsCancerInjectionInhibitorinhibitorinhibit

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