1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Centmitor-1

Centmitor-1 (Cent-1) is a mitotic arrest inducer. Centmitor-1 modulates microtubule plus-ends and reduced microtubule dynamics. In cells, Centmitor-1 causes mitotic arrest characterized by chromosome alignment defects, multipolar spindles, centrosome fragmentation, and activated spindle assembly checkpoint.

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Centmitor-1 Chemical Structure

Centmitor-1 Chemical Structure

CAS No. : 331749-88-3

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Description

Centmitor-1 (Cent-1) is a mitotic arrest inducer. Centmitor-1 modulates microtubule plus-ends and reduced microtubule dynamics. In cells, Centmitor-1 causes mitotic arrest characterized by chromosome alignment defects, multipolar spindles, centrosome fragmentation, and activated spindle assembly checkpoint[1].

Molecular Weight

450.28

Formula

C22H16BrN3O3

CAS No.
SMILES

O=C1C2=C(N(CC(N/N=C/C3=CC=C(C(Br)=C3)O)=O)C4=C1C=CC=C4)C=CC=C2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Centmitor-1
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HY-124519
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