2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. Cevoglitazar

Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research.

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Cevoglitazar Chemical Structure

Cevoglitazar Chemical Structure

CAS No. : 839673-52-8

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Based on 1 publication(s) in Google Scholar

Cevoglitazar Related Antibodies

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research[1].

IC50 & Target[1]

PPARα

 

PPARγ

 

Molecular Weight

558.53

Formula

C27H21F3N2O6S
CAS No.
SMILES

O=C([C@@H]1N(S(=O)(C2=CC=C(OCC3=C(C)OC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2)=O)C5=C(C=CC=C5)C1)O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cevoglitazar Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cevoglitazar839673-52-8LBM-642LBM642LBM 642PPARPeroxisome proliferator-activated receptorsOrallyPPARαPPARγfood intakefasting plasma insulinobesediabetesobesityInhibitorinhibitorinhibit

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