2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. Cevoglitazar

Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research.

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Cevoglitazar Chemical Structure

Cevoglitazar Chemical Structure

CAS No. : 839673-52-8

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Based on 1 publication(s) in Google Scholar

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research[1].

IC50 & Target[1]

PPARα

 

PPARγ

 

Molecular Weight

558.53

Formula

C27H21F3N2O6S
CAS No.
SMILES

O=C([C@@H]1N(S(=O)(C2=CC=C(OCC3=C(C)OC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2)=O)C5=C(C=CC=C5)C1)O
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Purity & Documentation
References
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Cevoglitazar Related Classifications

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Keywords:

Cevoglitazar839673-52-8LBM-642LBM642LBM 642PPARPeroxisome proliferator-activated receptorsOrallyPPARαPPARγfood intakefasting plasma insulinobesediabetesobesityInhibitorinhibitorinhibit

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