2. Membrane Transporter/Ion Channel
  3. CFTR
  4. CFTR corrector 13

CFTR corrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector (EC50=3.14 μM). CFTR corrector 13 enhances the function of CFTR channels, especially when used in combination with Lumacaftor (HY-13262), it can produce a dose-dependent increase in CFTR function. CFTR corrector 13 can be used in the study of cystic fibrosis (CF) and other CFTR-related diseases.

For research use only. We do not sell to patients.

CFTR corrector 13 Chemical Structure

CFTR corrector 13 Chemical Structure

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CFTR corrector 13 Related Antibodies

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Description

CFTR corrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector (EC50=3.14 μM). CFTR corrector 13 enhances the function of CFTR channels, especially when used in combination with Lumacaftor (HY-13262), it can produce a dose-dependent increase in CFTR function. CFTR corrector 13 can be used in the study of cystic fibrosis (CF) and other CFTR-related diseases[1].

Molecular Weight

537.03

Formula

C27H25ClN4O4S
SMILES

CC1=CC(CN2C(C(OCC)=O)=C(Cl)C3=C2C4=NC(NS(C5=CC=CC=C5)(=O)=O)=NC=C4CC3)=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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CFTR corrector 13 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CFTR corrector 13CFTR corrector13CFTR corrector-13CFTRCystic fibrosis transmembrane conductance regulatorCystic FibrosisCorrectorInhibitorinhibitorinhibit

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CFTR corrector 13
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HY-161894
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