2. Membrane Transporter/Ion Channel
  3. CFTR
  4. CFTR corrector 14

CFTR corrector 14 (Compound SVQ26) is a class 3 corrector for cystic fibrosis transmembrane conductance regulator (CFTR), that promotes the CFTR activity (EC50 of 3.08 μM with presence of C1 class corrector VX-809). CFTR corrector 14 regulates the mutant-caused misfolding and impaired function of the CFTR protein. CFTR corrector 14 can be used in research about cystic fibrosis.

For research use only. We do not sell to patients.

CFTR corrector 14 Chemical Structure

CFTR corrector 14 Chemical Structure

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CFTR corrector 14 Related Antibodies

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Description

CFTR corrector 14 (Compound SVQ26) is a class 3 corrector for cystic fibrosis transmembrane conductance regulator (CFTR), that promotes the CFTR activity (EC50 of 3.08 μM with presence of C1 class corrector VX-809). CFTR corrector 14 regulates the mutant-caused misfolding and impaired function of the CFTR protein. CFTR corrector 14 can be used in research about cystic fibrosis[1].

Molecular Weight

646.35

Formula

C26H22Br2N4O4S
SMILES

BrC1=CC(CN2C(C(OCC)=O)=C(Br)C3=C2C4=NC(NS(C5=CC=CC=C5)(=O)=O)=NC=C4CC3)=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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CFTR corrector 14 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CFTR corrector 14CFTR corrector14CFTR corrector-14CFTRCystic fibrosis transmembrane conductance regulatorcystic fibrosisCFmisfoldingInhibitorinhibitorinhibit

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