2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Chloropurine riboside

Chloropurine riboside  (Synonyms: 6-Chloropurine riboside)

Cat. No.: HY-W007791 Purity: 99.93%
SDS COA Handling Instructions

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Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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Chloropurine riboside Chemical Structure

Chloropurine riboside Chemical Structure

CAS No. : 5399-87-1

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Chloropurine riboside Related Antibodies

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Description

Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
> 200 μM
Compound: 7
Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
[PMID: 17766124]
Huh-7 EC50
31 μM
Compound: 7
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
[PMID: 17766124]
Vero IC50
48.7 μM
Compound: 1
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
[PMID: 17336519]
Molecular Weight

286.67

Formula

C10H11ClN4O4
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 99.93%

SDS (393 KB)

COA (256 KB) HNMR (122 KB) RP-HPLC (250 KB)

Handling Instructions (2659 KB)
References
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Chloropurine riboside Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chloropurine riboside5399-87-16-Chloropurine ribosideNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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